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you are using an outdated browser. please upgrade your browser or activate google chrome frame to improve your experience. français (fr) english (en) en français english research people jobs news appel à candidature pour la future direction du gred call for a new research group leader phd defense: cristiana dondi les mardis du gred - juin 2018 dna methylation : a new actor in cml biology genome plasticity: example of 5s ribosomal rna genes gred symposium : "les surpises du vivant" cymbopogon citratus and cancer: when citronella is a repellent not only for mosquitoes… recombination machinery compensates telomere loss in the absence of telomerase. how to turn a football into a rugby ball? line fishing... with the new bioinformatics tool clifinder sponsors news meetings phd defenses conferences research thematics thematic 1: genome dynamics and epigenetic control thematic 2: reproduction and development in health and disease thematic 3: endocrinology, signalling and cancer facilities anipath confocal imaging facility current cell and tissue culture facilities fly facility transgenic mouse facility staff administration bioinformatics support plants support technical staff teaching doctoral school greetings from the 3d fish summer school master génétique et physiologie recherche job phd fellowships postdoctoral fellowships permanent positions tutelages research thematics thematic 1: genome dynamics and epigenetic control leaders: arnaud mathieu probst / tatout vaury / brasset waltzer white / gallego thematic 2: reproduction and development in health and disease leaders : chazaud drevet / saez jagla mirouse sapin thematic 3: endocrinology, signalling and cancer leaders : baron / lobaccaro martinez / val volle news call for a new research group leader the gred wishes to recruit a new independent leader to form a group within the scientific spectrum of the gred. the gred will provide laboratory space (50m 2 ) and free access to state-of-the-art technological platforms (cell/tissue culture, facs, imaging/live imaging, histology). the successful candidates will have full access to transgenic plant and animal (mouse, drosophila, arabidopsis) and bioinformatics facilities and will benefit of administrative support. facilities for high-throughput sequencing, mass spectrometry, proteomics, electron microscopy and radiobiology are available on the multidisciplinary medical school campus. read more appel à candidature pour la future direction du gred le gred lance un appel à candidature pour recruter sa future directrice ou futur directeur, pour une prise de fonction en janvier 2021 read more phd defense: cristiana dondi cristiana dondi (team “diversification of muscle and heart cells in normal and pathological conditions ”) will defend her thesis entitled: "molecular and functional analysis of cardiac diversification by cell specific translatomic approaches in drosophila melanogaster" friday the 8 th of june 2018 at 1.30 pm amphi 2a , medical school read more les mardis du gred - juin 2018 12h45 – 13h45 faculté de médecine amphi limagne (crbc rdc) read more dna methylation : a new actor in cml biology chronic myeloid leukemia (cml), a cancer of the white blood cell, results from a translocation event that ultimately leads to the production of bcr-abl1, a chimeric oncoprotein that promotes cml by aberrantly phosphorylating target proteins. nonetheless, this event on its own, cannot account for an increasing number of clinical observation suggesting the involvement of other pathways, among which dna methylation alteration emerges as a relevant candidate. on that basis the teams of marc berger (chu, clermont-ferrand) and philippe arnaud have characterized for the first time the dna methylation patterns of cml cell subsets (immature and mature cells) isolated form the same clone during the early stage of the disease, before any treatment ( maupetit-méhouas, court, bourgne et al. ,). altogether, this collaborative study demonstrated that dna methylation abnormalities exist at early stages of cml and can affect the transcriptional landscape of malignant cells. these observations paved the way for new therapeutic strategies based on epigenetic drugs. read more cnet 2018: registration is open the 21st annual meeting organized by the french research community working on transposable elements (cnet 2018), organized this year by the gred, will be held in clermont-ferrand on 2-4 july 2018. this conference will cover all aspects of transposable element biology, including molecular mechanisms, cellular defense pathways, physiological impact on organisms, evolution of genomes and populations, and ecology. for more details (programm, registration ) it's here . read more embo workshop "plant genome stability and change" this embo workshop represents the sixth international meeting on molecular and cellular mechanisms underlying stability, variability and modification of plant genomes. it will be held at the ipk gatersleben, germany, june 3-6, 2018. for more details (programm, registration ) it's here. read more genome plasticity: example of 5s ribosomal rna genes the genes coding 5s ribosomal rnas (critical components of the ribosomes, the cellular machineries translating mrna into proteins) are highly repeated in the genome, which allows the production of large quantities of these rrnas. in their last study ( simon et al., 2018 ), the team of aline probst and christophe tatout revealed an important variation in number and expression of 5s rrna genes between different ecotypes of arabidopsis thaliana . read more gred symposium : "les surpises du vivant" the wednesday 16th of may, the gred organizes its symposium "les surprises du vivant". amphitheater limagne, crbc building , faculté de médecine to the programm click on "read more ".... read more cymbopogon citratus and cancer: when citronella is a repellent not only for mosquitoes… through a real bilateral collaboration, drs. silvère baron’s et and jean-marc lobaccaro’s team nuclear receptor and prostate diseases and pr. jacques simpore’s team (laboratoire de biologie moléculaire et de génétique, université de ouagadougou, burkina faso), have identified medicinal plants of the burkina faso pharmacopeia that could be used in the future in cancer treatment ( bayala et al., 2018 ). read more in a few words... the gred is a research center at clermont-ferrand , auvergne rhône alpes region of france. created in 2008, the gred is supported by the university clermont auvergne (uca) , the cnrs (umr6293) and the inserm (u1103). the center is composed of 14 research groups (totalling 147 people in december 2017) based at the centre de recherche bio-clinique (crbc) on the campus ... read more gred faculté de médecine 28, place henri dunant bp 38 - 63001 clermont-ferrand +33(0)4 73 17 81 70 http://www.gred-clermont.fr contact us news call for a new research group leader appel à candidature pour la future direction du gred phd defense: cristiana dondi les mardis du gred - juin 2018 dna methylation : a new actor in cml biology cnet 2018: registration is open embo workshop "plant genome stability and change" genome plasticity: example of 5s ribosomal rna genes gred symposium : "les surpises du vivant" cymbopogon citratus and cancer: when citronella is a repellent not only for mosquitoes… links latest publications explore publications research thematic 1: genome dynamics and epigenetic control thematic 2: reproduction and development in health and disease thematic 3: endocrinology, signalling and cancer facilities anipath confocal imaging facility current cell and tissue culture facilities fly facility transgenic mouse facility teaching doctoral school greetings from the 3d fish summer school master génétique et physiologie recherche jobs phd fellowships postdoctoral fellowships permanent positions copyright © gred 2014 • made with love by tailordev from l'agence comsource .
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